Glioblastoma is currently considered the most invasive type of brain tumor. Therefore, it is important to diagnose and treat patients at early stages, preferably by an experienced specialist. Leading the glioblastoma treatment and care, Dr. Kumardeep Dutta Choudhury is an experienced glioblastoma cancer specialist in Delhi, offering technologically advanced treatment and supportive care.
What is Glioblastoma?
Glioblastoma multiforme (GBM) is a high-grade astrocytoma, a rapidly growing type of primary brain tumor. This is the most frequently observed and the most lethal of all the primary adult brain tumors. The glioblastomas are invasive and thus difficult to cure, and they tend to relapse regardless of compliance with therapy.
Symptoms of Glioblastoma
These signs of glioblastoma may depend on the size and site of the brain tumor. It is important for intervention to be initiated as early as possible. If you observe any of these symptoms, do not wait to get them advanced; visit the best glioblastoma oncologist in Delhi.
Persistent Headaches
Recurring headaches have progressively worsened and become aggressive with lifting or coughing.
Seizures
Even in patients without previous seizures, new-onset seizures are indicative of brain pathology of a certain type.
Behavioural Changes
These may include changes in thinking, memory, orientation, mood, personality, activity level, and speech. They often include memory problems, problems making decisions, an inability to concentrate, mood swings, or depression.
Neurological Deficits
Paralysis or tingling sensation on one side of the body. These include problems with speech and balance or vision impairments.
Nausea and Vomiting
It may be frequent due to raised pressure inside the cerebral area.
Treatment Options for Glioblastoma
Glioblastoma, the most malignant primary brain tumor, is a clinically diverse and challenging disease that also needs a multimodal therapeutic strategy. Though it is still difficult to treat, present-day medical procedures slow the tumor’s growth, reduce its effects on the body, and increase life expectancy. Here is an elaborate analysis of the treatment procedures:
Surgery
The first intervention in treating glioblastoma is surgery, which removes as much of the tumor as possible without impairing normal brain functioning. Specialists in central nervous system surgery and neurosurgeons, for example, use a craniotomy to reach the growth and expel it. Accurate technology improvements such as intraoperative MRI and neuronavigation are utilized in some instances. Since the tumor is invasive, meaning it cannot be operated out completely, the process minimizes the size of the tumor, thus reducing the pressure that is exerted on the brain and enhancing the effectiveness of other treatments that are carried out.
Radiation Therapy
Radiation therapy is applied after surgery to eliminate left-behind cancer cells and control the progression of the disease. The tumor is irradiated using either high-energy X-rays or a proton beam. Sometimes, radiation may take several weeks, and it may be given in short sessions daily.
Chemotherapy
In glioblastoma treatment, the oral chemotherapy drug temozolomide, commonly known as TMZ, is often used. Temozolomide has a mechanism of action that interferes with the DNA of the glioblastoma, causing those cells to stop growing or dividing. Usually given during and after radiation treatment for optimum results. Research has established that administering Temozolomide in conformity with radiation boosts survival and enhances the quality of life.
Targeted Therapy
Bevacizumab (Avastin) is a drug that works by blocking the action of vascular endothelial growth factor (VEGF), which causes the formation of blood vessels that supply the tumor. It reduces manifestations such as swelling and allows the patient to alleviate pain and discomfort, but it is not a cure.
Emerging Therapies
Immunotherapy: It stresses the increased activity of the body’s immune response in recognizing glioblastoma cells.
Tumor Treating Fields (TTF): A completely new approach concerning applying weak electric currents to interfere with cell division of cancer cells.
Clinical Trials: Most glioblastoma patients seek clinical trials that have new treatments, such as gene therapy and other personalized medicine treatment methods.
Glioblastoma should be managed by one of the most qualified healthcare providers. Dr. Kumardeep Dutta Choudhury is the best glioblastoma cancer specialist in Delhi. He uses specialized treatment for every patient, depending on his or her circumstances.
Glioblastoma may be thought to originate from genetic changes to the brain cells in most cases. Although specific causes are not well understood, causes associated with the disease entail age, radiation, and family history of brain cancer.
Today, glioblastoma is regarded as untreatable, though certain therapeutic interventions can prolong life and enhance its quality. It is very important to diagnose the case at an early stage and avail of modern health care services.
The mean outcome duration with conventional treatments is between 12 and 18 months. However, new developments in therapies or treatment techniques may increase the span of the disease in a particular survivor.
Some patients use clinical trials, diet alterations, and complementary and alternative medicine in addition to mainstream medicine. It is always important to consult a renowned glioblastoma cancer specialist in Delhi about these options.
Establishing the diagnosis of some patients requires MRI or CT scans and then a biopsy to determine the type and grade of the tumor.
Cancer
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